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| DIETARY SUPPLEMENTS AND HEART HEALTH In 2005, more than 650,000 people died from heart disease, accounting for 27% of the deaths in the United States, making it the leading cause of death for both men and women. The development of cardiovascular disease is very complicated, and it is affected by multiple factors, including elevated cholesterol and triglycerides, coagulation factors, platelet aggregation, glucose metabolism, and smoking. To maintain good "heart health", the combination of a good diet, exercise, and no smoking is essential. For patients who need additional therapy beyond lifestyle modifications, doctor-prescribed medications are available and some dietary supplements may be considered. Some of the most common supplements used to improve heart health will be discussed. As with any over-the-counter products, it is very important to check with your physician before you begin taking any supplements as well as telling them of any you are currently using. Omega-3 Fatty Acids: There is good evidence supporting the conclusion that omega-3 fatty acids from fish or fish oil supplements significantly reduce triglyceride levels. They also may cause small improvements in high-density lipoprotein (HDL; "good cholesterol"). Increased levels of low-density lipoprotein (LDL; "bad cholesterol") were also seen, however. Multiple studies report a reduction in secondary events associated with cardiovascular disease, including reductions in nonfatal and fatal heart attacks and sudden cardiac (heart-related) death. It is important to note that patients in these trials were also taking prescription drugs for the heart and were being routinely evaluated by a physician. The most significant side effect associated with omega-3 fatty acids is bleeding, although this is seen more often with excessive use. Patients who are also taking any medication that may thin the blood should check with their primary care provider before beginning any regular supplementation with omega-3 fatty acids. Upset stomach, diarrhea, and nausea were also common with the use of fish oil supplements. The American Heart Association (AHA) has released recommendations for the use of omega-3 fatty acids for the treatment of elevated triglyceride levels. For patients without coronary heart disease, the AHA recommends eating fish at least twice a week. For patients with coronary heart disease, the AHA recommends consumption of about 1 gram per day of omega-3 fatty acids. These patients may consider using supplements, such as fish oils. For patients who need to significantly lower triglyceride levels, supplementation with 2 to 4 grams per day of fish oil is recommended. Lastly, vitamin E is essential for the metabolism of omega-3 fatty acids, and with long-term use of fish oil supplements, extra vitamin E is needed. Because of this, many fish oil supplements contain additional amounts of vitamin E. Garlic: Garlic is one of the oldest recorded remedies used to treat disease. In recent clinical trials, the most important effects of garlic are those of mild reductions in cholesterol and reduced platelet clotting. The decrease in platelet clotting leads to its most common side effect, bleeding. Other side effects include asthma flares, dizziness, sweating, bad breath, body odor, headache, itching, fever, chills, and runny nose. The current recommended dose for garlic supplementation is 200 to 300 mg of garlic extract 3 times a day (600-900 mg/day). If taken as part of the diet, 2 to 5 grams of fresh garlic is recommended daily. Coenzyme Q10: Coenzyme Q10 (CoQ10) is a substance produced by the human body that is necessary for the normal function of cells. It has been noted that levels of CoQ10 decrease with age and are lower in some patients with chronic conditions such as cardiovascular disease. There is a lot of controversy surrounding the use of CoQ10 supplements. The only clear indication is in patients who do not have enough CoQ10. Other promising areas of research include blood pressure and some other heart conditions. Few side effects have been noted and include nausea, vomiting, rash, insomnia, headache, and flu-like symptoms. Organ damage due to lack of oxygen and blood flow has been noted in patients with heart disease during vigorous exercise. Additionally, CoQ10 supplementation may reduce the effectiveness of warfarin (Coumadin), a blood-thinning medication. It may also affect thyroid hormone levels and change your response to levothyroxine (Synthroid). Finally, CoQ10 may interact with antiviral medications and some medications used to treat HIV. The recommended dose ranges from 50 to 1200 mg/day in divided doses. The cornerstone of any effort made for the prevention of heart disease is eating healthy, exercising, and not smoking. In fact, quitting smoking is the single most important factor patients can change to reduce the risk of developing or worsening heart disease. The AHA recommends that healthy people get their nutrients by eating a variety of foods, in moderation, rather than by taking supplements. Emphasis should be placed on fruits, vegetables, and whole grains. In nonsmoking patients with a healthy diet who exercise regularly, supplementation with certain substances, especially omega-3 fatty acids, can be associated with reductions in cardiovascular disease. Most importantly, a physician should be consulted prior to beginning any supplement, especially for those patients with known heart disease or who are already taking prescription drugs. Combating Fatigue and Drowsiness Everyone has felt tired or sleepy during the day. Undue tiredness may be caused by a number of serious medical conditions, so if simple advice or OTC products containing caffeine do not help, it is wise to see a physician. Before you take any medications for fatigue and drowsiness, you may wish to try some relatively easy solutions. You should not go to bed and arise at odd times or at different times each day. The best advice is to set a time for going to bed and also for arising and try to stick to them as much as possible. Everyone has experienced the "fun" of staying up till 4 am or later and then sleeping in until noon the next day. Even 8 hours of sleep cannot fool your body into normalcy, and you will feel the effects of your altered schedule the next day. In addition, strive to get at least 7 to 8 hours of sleep a night. Trying to get through the next day without adequate sleep leads to daytime drowsiness that is a major cause of fatal automobile accidents. Avoid stimulants such as caffeine or oral nasal decongestants (e.g., Sudafed) too close to bedtime, as the stimulant effect may not allow you to drop off to sleep at the right times, leaving you fatigued the following day. You should always eat a healthy, balanced diet and drink sufficient water to keep fully hydrated. Avoid all alcohol, nicotine, and drugs of abuse. If you habitually drink caffeine-containing soft drinks, coffee, or tea, try to reduce the amount or eliminate them completely to determine whether they are responsible for a tired feeling. You should also be aware of any medications you are taking that may cause drowsiness, such as antihistamines, antihypertensives, corticosteroids, diuretics, and sleep aids. One method to reduce fatigue is to reduce life stresses. It may be necessary to change from a job that causes severe stress to one that allows a more relaxing day of work. When you have spare time, do not spend it playing high-stress video games that require split-second timing and fast reflexes. Instead, go for a walk, read a book, or have a pleasant conversation with family and friends. If you are caught in a relationship that is fraught with problems, deal with them directly or end the relationship. The only pharmacy product proven safe and effective in helping fight fatigue and drowsiness is caffeine, found in such OTC products as Vivarin and NoDoz. Each caplet or tablet contains 200 mg of caffeine. Take one dose not more often than every 3 to 4 hours. These products are only safe for those aged 12 years and above. They are not a substitute for healthy sleep and should never be used to keep you awake all night. They should not be used if you are pregnant or breastfeeding without speaking to your physician first. Avoid the use of the popular energy drinks. Virtually all contain ingredients of unknown safety and effectiveness, such as herbs and dietary supplements. One contains such unproven ingredients as ginkgo, guarana, inositol, L-carnitine, ginseng, and milk thistle. Using products such as these is a risky gamble with your health, since they can have adverse effects and are not proven to provide a safe boost of energy. FLU SEASON: TAKING CARE OF A SICK PERSON IN YOUR HOME The main way that influenza viruses are thought to spread is from person to person in respiratory droplets of coughs and sneezes. This can happen when droplets from a cough or sneeze of an infected person are propelled through the air and deposited on the mouth or nose of people nearby. Influenza viruses may also be spread when a person touches respiratory droplets on another person or an object and then touches their own mouth or nose (or someone else's mouth or nose) before washing their hands. When providing care to a household member who is sick with influenza, the most important ways to protect yourself and others who are not sick are to: Keep the sick person away from other people as much as possible; especially others who are at high risk for complications from influenza. Remind the sick person to cover their coughs, and clean their hands with soap and water or an alcohol-based hand rub often, especially after coughing and/or sneezing. Have everyone in the household clean their hands often, using soap and water or an alcohol-based hand rub. Children may need reminders or help keeping their hands clean. Ask your health care provider if household contacts of the sick person - particularly those contacts who may be pregnant or have chronic health conditions- should take antiviral medications such as Tamiflu or Relenza to prevent the flu. If you are in a high risk group for complications from influenza, you should attempt to avoid close contact (within 6 feet) with household members who are sick with influenza. If close contact with a sick individual is unavoidable, consider wearing a facemask or respirator, if available and tolerable. Infants should not be cared for by sick family members.
Placement of the sick person: Keep the sick person in a room separate from the common areas of the house. For example, a spare bedroom with its own bathroom, if that's possible. Keep the sickroom door closed. Unless necessary for medical care or other necessities, people who are sick with an influenza-like-illness should stay home and keep away from others as much as possible, including avoiding travel, for at least 24 hours after fever is gone except to get medical care or for other necessities. (Fever should be gone without the use of a fever-reducing medicine). This is to keep from making others sick. Children, especially younger children, might potentially be contagious for longer periods. If persons with the flu need to leave the home (for example, for medical care), they should wear a facemask, if available and tolerable, and cover their nose and mouth when coughing or sneezing Have the sick person wear a facemask - if available and tolerable - if they need to be in a common area of the house near other persons. If possible, sick persons should use a separate bathroom. This bathroom should be cleaned daily with household disinfectant.
Protect other persons in the home: The sick person should not have visitors other than caregivers. A phone call is safer than a visit. If possible, have only one adult in the home take care of the sick person. People at increased risk of severe illness from flu should not be the designated caretaker, if possible. If you are in a high risk group for complications from influenza, you should attempt to avoid close contact (within 6 feet) with household members who are sick with influenza. If close contact with a sick individual is unavoidable, consider wearing a facemask or respirator, if available and tolerable. Avoid having sick family members care for infants and other groups at high risk for complications of influenza. All persons in the household should clean their hands with soap and water or an alcohol-based hand rub frequently, including after every contact with the sick person or the person's room or bathroom. Use paper towels for drying hands after hand washing or dedicate cloth towels to each person in the household. For example, have different colored towels for each person. If possible, consideration should be given to maintaining good ventilation in shared household areas (e.g., keeping windows open in restrooms, kitchen, bathroom, etc.). Antiviral medications can be used to prevent the flu, so check with your health care provider to see if some persons in the home should use antiviral medications.
If you are the caregiver: Avoid being face-to-face with the sick person. When holding small children who are sick, place their chin on your shoulder so that they will not cough in your face. Clean your hands with soap and water or use an alcohol-based hand rub after you touch the sick person or handle used tissues, or laundry. Talk to your health care provider about taking antiviral medications to prevent the caregiver from getting the flu. If you are at high risk of influenza associated complications, you should not be the designated caretaker, if possible. If you are in a high risk group for complications from influenza, you should attempt to avoid close contact (within 6 feet) with household members who are sick with influenza. Designate a person who is not at high risk of flu associated complications as the primary caretaker of household members who are sick with influenza, if at all possible. If close contact with a sick individual is unavoidable, consider wearing a facemask or respirator, if available and tolerable. Monitor yourself and household members for flu symptoms and contact a telephone hotline or health care provider if symptoms occur.
Household Cleaning, Laundry, and Waste Disposal: Throw away tissues and other disposable items used by the sick person in the trash. Wash your hands after touching used tissues and similar waste. Keep surfaces (especially bedside tables, surfaces in the bathroom, and toys for children) clean by wiping them down with a household disinfectant according to the directions on the product label. Linens, eating utensils, and dishes belonging to those who are sick do not need to be cleaned separately, but importantly these items should not be shared without washing thoroughly first. Wash linens (such as bed sheets and towels) by using household laundry soap and tumble dry on a hot setting. Avoid "hugging" laundry prior to washing it to prevent contaminating yourself. Clean your hands with soap and water or alcohol-based hand rub right after handling dirty laundry. Eating utensils should be washed either in a dishwasher or by hand with water and soap.
For more information, The Centers for Disease Control and Prevention (CDC) Hotline (1-800-CDC-INFO) is available in English and Spanish, 24 hours a day, 7 days a week. 
Irritable Bowel Syndrome Irritable bowel syndrome (IBS) is a chronic condition characterized by abdominal pain or discomfort with recurrent episodes of such symptoms as diarrhea, bloating, constipation, gas and bloating, and urgency. The patterns of IBS symptoms and their severity vary widely among patients. Symptoms are usually classified as diarrhea-predominant, constipation-predominant, or alternating. IBS is not the result of organic disease and no physical or structural abnormalities are associated with IBS. Patients may develop IBS symptoms after a gastrointestinal infection, other major illness, traumatic events, or stressful life situations. The neurological connections between the brain and the gut are known to be an important factor in regulation of bowel motility, absorption, and sensitivity. In addition, imbalances in the normal gut bacteria have been found in many patients and may be responsible for IBS symptoms. There is no test or specific pathology to identify IBS. The patient with IBS should meet Rome criteria for the past 3 months, have had symptoms for at least 6 months, and not have warning signs that may indicate organic disease. Warning signs that may indicate diseases other than IBS include rectal bleeding, anemia, weight loss, fever, family history of colon cancer, onset of symptoms after 50 years of age, and a major change in symptoms. Treatment options for IBS are targeted at normalizing bowel habits and reducing abdominal discomfort. Most patients find that certain foods may trigger episodes of IBS and learn to avoid them to reduce symptoms. Traditional over-the-counter medications for diarrhea or constipation are sometimes recommended for individual symptoms, but may have no effect on abdominal pain or bloating. Several prescription medications that affect the "brain-gut" connection have been developed for IBS, depending on the type of symptoms the patient is experiencing. These include alosetron (for diarrhea-predominant IBS) and tegaserod or lubiprostone (for constipation-predominant IBS). Low doses of antidepressants are sometimes effective for abdominal pain in patients with IBS, because of the neurological connections between the brain and the gut. These agents are generally given at lower doses than would be effective for mood disorders. Symptoms of bloating and gas have been shown to be affected by agents that change the balance of bacteria in the gut, such as antibiotics. Probiotic foods and supplements have received considerable promotion for improvement of intestinal health. The quality of these claims for probiotic products is difficult to ascertain unless the microorganisms have been standardized, identified to the strain level, and tested in randomized clinical trials. Recommendations for probiotics for patients with IBS should be supported by data from studies specifically in this population. The probiotic supplement Bifidobacterium infantis 35624 has been found effective in randomized, placebo-controlled clinical trials for global IBS symptoms, as well as the individual symptom of bloating in men and women with all subtypes of IBS.  How to Fight Lactose Intolerance Lactose intolerance means that you are unable to fully digest the milk sugar (lactose) found in dairy products. It can cause uncomfortable and embarrassing digestive problems. Fortunately, you can control your symptoms through a carefully chosen diet. Milk, cheese, and other dairy products are made of a sugar called lactose (milk sugar). Lactose is made of two simpler sugars hooked together. It is broken down by lactase, an enzyme that turns it into the simpler sugars that your body can absorb to use for energy. Some patients lack the enzyme lactase in their small intestine. They cannot digest milk and dairy products, and they are said to be lactose intolerant. In these cases, the lactose moves through the intestines without being broken down, as it cannot be used for energy. This causes a host of embarrassing problems. What symptoms make you think that lactose intolerance is a problem? Symptoms usually begin 30 to 120 minutes after drinking milk or eating dairy products. The stomach rumbles and the abdomen feels swollen and uncomfortable. Nausea, abdominal pain and cramping, excess gas, and watery diarrhea are all common. However, it depends on how much of the offending food and drink was ingested. Lactose intolerance is most often a result of one's genetic background. While many people of northern European descent can drink milk as adults without experiencing any problems, most people of African, Asian, American Indian, and Hispanic heritage cannot. In some cases, however, lactose intolerance can also occur after a person has a viral infection, experiences an episode of diarrhea, or undergoes certain intestinal surgeries. In these cases, the person may eventually be able to drink milk again without incident. A true milk allergy is a dangerous disorder in which you may suffer a severe allergic reaction and possibly die if you ingest milk. Milk must be completely eliminated from the diet. One way to prevent the symptoms of lactose intolerance is to reduce the amount of lactose ingested. Thus, you must avoid or reduce all sources of lactose, such as milk, cream, half-and-half, ice cream, and cheeses. You must also read all food and drink labels carefully. You may discover that lactose (i.e., milk sugars, whey, casein, caseinate, or nonfat dry milk solids) is included in dips, breads, sherberts, frozen dairy desserts, puddings, instant potatoes, salad dressings, prepared soups, butter, and canned/frozen fruits and vegetables. Actually, many people may still be able to ingest some of these products. The key is to know your own individual tolerance. Your pharmacist can help you determine this level. Several manufacturers market lactose-free milks that may prevent symptoms. Some are also calcium-enriched to allow you to obtain adequate amounts of this vital nutrient. You may also choose from milk substitutes, such as soy-based or rice-based products. Pharmacies also sell several products that contain lactase, the enzyme that you are lacking. Several of these are marketed under the Lactaid trade name. You should take the recommended dose at the same time as the offending food or drink is ingested. This may break down the lactose for you and prevent symptoms.  MYTHS AND FACTS ABOUT THE FLU AND COLDS Myth: You can catch the flu from a flu shot.
Fact: The flu vaccine is made from an inactivated virus, so you cannot get the flu from a flu shot. Some people may be sore at the spot where the vaccination was injected, and in a few cases, may develop a fever, muscle aches and feel unwell for a day or two. In very rare cases when a person is allergic to the vaccine, there may be an immediate reaction. Myth: One kind of flu is the "stomach flu". Fact: About one out of three people with the flu may have an upset stomach, but this is rarely the main symptom of the flu. Other viruses and bacteria, and food poisoning are more common causes of nausea, vomiting and diarrhea. Myth:There is nothing you can do once you get sick with the flu except stay home in bed. Fact: Antivirals, when started within 2 days after flu symptoms appear, can reduce the duration of the illness and the severity of symptoms. Symptom relief medications and rest are other options that can also help to minimize the discomfort associated with flu symptoms. Myth: You can catch the flu or a cold from going outdoors in cold weather. Fact: The flu and colds are more common in the winter months because that is when the viruses spread across the country. It has nothing to do with being outside in cold weather. Myth: Large doses of Vitamin C can keep you from catching the flu or a cold, or will quickly cure them. Fact: These claims have not been proven. Still, it is important to one's overall health to consume the minimum daily requirement of Vitamin C. Myth: "Feed a cold and starve a fever (flu)". Fact: This is definitely not a good idea in either case. You need more fluids than usual when you have the flu or a cold. Drink plenty of water and juice, eat enough food to satisfy your appetite and drink hot fluids to ease your cough and sore throat. Myth: Herbal remedies are an effective treatment for colds. Fact: Echinacea and other herbs are getting a lot of publicity as cold remedies. Zinc lozenges are also said to cure colds quickly. To date, none of these claims are solidly supported by scientific studies. Myth: Chicken soup and hot toddies are effective treatments for the flu or colds. Fact: A bowl of chicken soup is a popular home remedy. While hot liquids can soothe a scratchy throat or cough, chicken soup has no special power to cure the flu or a cold. As for hot toddies, another folk remedy, any beverage containing alcohol should be avoided when you are sick. 
In the United States, about 30,000 people suffer from cystic fibrosis, with 1,000 new cases diagnosed each year. Although years ago most children diagnosed with the disease did not reach elementary school age, today patients are likely to live into their late 30's and beyond. Cystic fibrosis is an inherited disease caused by a recessive gene. There are 10 million carriers of the cystic fibrosis gene in the U.S., and many are not aware they carry it because they have no symptoms of the disease. This gene changes an important protein that controls the movement of salt and fluid in and out of cells, causing an imbalance of salt in the body. This results in thick mucus that clogs the passages in the lungs and pancreas, and in salty sweat that can cause problems in hot environments. Frequent cough, respiratory infections, shortness of breath, wheezing, and sinus infections are the primary symptoms of cystic fibrosis. As respiratory complications are the most common cause of death in these patients, aggressive treatment to keep the lungs clear of mucus and free of infection is critical. The mucus also stops the digestive enzymes from moving out of the ducts of the pancreas. These enzymes are needed to break down fat and protein in the intestines, so without them, nutrients and many vitamins in food are not absorbed. Often patients have diarrhea or greasy stools. Cystic fibrosis causes patients to become thin and malnourished even though they have good appetites. Enzyme supplements must be taken with every meal to help digestion and maintain nutrient absorption. An inflammation of the pancreas, called pancreatitis, can result when the pancreatic ducts are blocked by mucus. With an increase in the amount of salt lost in the sweat, a hot environment can easily cause dehydration. Diagnosis is done with a simple test of the amount of salt in the patient's sweat, called the sweat test. Blood tests to identify the defective gene that causes cystic fibrosis may also be ordered. Since patients have many chronic, low-grade respiratory and sinus infections, x-rays of the lungs and sinuses are used to determine if inflammation or scarring is present. A culture of the sputum can show if there are bacteria present in the lungs and helps determine which antibiotics would be best to treat an infection. The general goal of treatment is to minimize the complications of cystic fibrosis, since there is no cure at present. In order to keep the lungs healthy, infection-free, and clear of mucus, patients use daily chest physical therapy, exercise, and antibiotics. Chest physical therapy consists of pounding or clapping on the chest (percussion) to loosen the mucus, usually when the patient is sitting or lying in a position that will help the mucus drain (postural drainage). There are mechanical percussion machines that help loosen mucus, inflatable vests that help force the mucus out of the lungs, and breathing devices that cause vibrations to loosen the mucus. Exercise is also very helpful. Oral and inhaled antibiotics are used to control the chronic bacteria present in the mucus of the lungs, and IV antibiotics are used when serious respiratory infections occur. Other inhaled medications, such as mucolytics and hypertonic saline, can be used to thin out mucus and make it easier to cough out. High doses of ibuprofen can be used to lessen inflammation in the lungs. Although ibuprofen is available OTC, it should be prescribed since the drug has several side effects and blood levels must be monitored by a doctor. Digestive problems in cystic fibrosis are treated with the use of pancreatic enzyme supplements, taken before every snack and meal. These enzyme supplements help the body absorb the vitamins and nutrients in food and prevent malnutrition. Supplements of the fat-soluble vitamins (A, D, E, and K) are also needed to ensure enough are absorbed in the intestines. Some patients may have a feeding tube placed in their stomach overnight in order to receive liquid nutritional supplements. Patients with cystic fibrosis should be treated by specialists in the disease. Your pharmacist can answer any questions you may have about the medications used to control the symptoms of cystic fibrosis.

Glaucoma is the result of damage to the optic nerve, usually because of a fluid build-up that increases the pressure in the eye. However, not everyone with increased eye pressure will develop glaucoma, and some patients with normal eye pressure can develop optic nerve damage. Glaucoma can also occur when the pressure in the eye is normal; this condition is called normal-tension or low-tension glaucoma. This glaucoma is less common than those types caused by increased pressure in the eye, and it is not clear why the optic nerve suffers damage when the fluid pressure is not increased. Glaucoma can also be congenital, and early surgery on children born with glaucoma can often allow for the development of good vision. The biggest risk factor for glaucoma is an increase in eye pressure. Age is also an important risk factor for glaucoma, with an increased risk in most people after age 60 and for African-Americans after age 40. African-Americans and Mexican-Americans are more likely to develop glaucoma amd are more likely to become blind as a result. A family history of glaucoma makes it more likely a person will suffer from the condition in later years. Secondary glaucoma can be a result of eye injury, tumors, inflammation, eye surgery, or diseases such as hypertension, heart disease, low thyroid function, and diabetes. Even certain drugs can cause glaucoma, especially the long-term use of corticosteroids. In the case of closed-angle glaucoma, anything that allows the pupil to dilate (enlarge) can begin an attack. It is important to have regular eye exams and eye pressure measurements every two years after age 40 and every year after age 65, because slow increases in eye pressure and gradual damage to the optic nerve may go unnoticed. Eye exams should begin even earlier in African-Americans due to their higher risk of glaucoma. The diagnosis of glaucoma is made by an eye doctor using tests such as tonometry, photography, visual field tests, and pachymetry. Tonometry measures eye pressure using a puff of air or a flat cone that presses on the eyeball to flatten it. The eye doctor can also take a photograph of the optic nerve or use an ophthalmoscope to see through the pupil and into the back of the eye. Visual field testing involves a screen with small objects that come into view from various parts of the visual field and are recognized by the patient when they appear. This test can determine if there are parts of the visual field that are not clear. Pachymetry is an ultrasonic measurement of the thickness of the cornea, which is important in determining whether eye pressure is being accurately assessed. A combination of these tests is used to diagnose increased eye pressure and early damage to the optic nerve. The goal of all glaucoma treatment is to lower the intraocular pressure. Treatment for glaucoma includes eye drops, oral medications, laser therapy, and/or surgery. Eye drops that lower the production of fluid include beta-blockers (timolol, carteolol, and others), alpha-adrenergic drugs (apraclonidine, brimonidine), and carbonic anhydrase inhibitors (dorzolamide, brinzolamide). Each of these eye drops has systemic side effects, so they may not be best for everyone. Eye drops that increase the drainage of fluid in the eye include pilocarpine, epinephrine, and prostaglandin-like drugs such as bimatoprost, latanoprost, and others. These drugs also have their own set of side effects. Oral carbonic anhydrase inhibitors such as acetazolamide and methazolamide are used when eye drops are not able to lower eye pressure sufficiently. These drugs also have a variety of side effects.. Laser therapy works by increasing fluid drainage by shrinking part of the spongy filtering tissue, allowing the rest of the tissue to stretch and drain more easily. Another option is surgery, during which a hole in the spongy filter is created to help the fluid to flow out of the eye more easily. A small drainage tube may be inserted to maintain the drainage. Some doctors recommend vitamin supplements specially designed for eye health for their glaucoma patients.
The warm weather is finally upon us, and that means more aches and pains due to increased activity for many people. When you experience minor aches and pains such as a headache, toothache, or muscle ache, you can choose from hundreds of nonprescription analgesics or OTC pain medications for treatment. Each carries a set of labeled warnings that are vitally important to read before you purchase the product.
Before taking each dose of a nonprescription analgesic, you should always take the time to carefully review the product warnings. If you fail to read and understand each precaution, you may become one of the many hundreds of patients who suffer illness or even death from misuse. Each analgesic product will have clear instructions for which ages can safely use it. For instance, some children's acetaminophen products (e.g., Infants' Tylenol Concentrated Drops) will allow you to give them as young as 2 years of age. Other acetaminophen products such as tablets are more appropriate for older children. Aspirin has little legitimate use in children. It should never be given under the age of 3 years, but current wisdom advises against use in children at all due to its many dangers. One is the development of life-threatening Reye's syndrome. To help prevent Reye's syndrome, aspirin must not be given to children or teenagers who have or are recovering from chicken pox or flu-like symptoms. Early symptoms include changes in behavior, nausea, and vomiting. If you suspect Reye's syndrome, the child must immediately be taken to an emergency room. Ibuprofen (e.g., Advil, Motrin) can be given to children as young as 6 months, if the infants' concentrated drops are chosen. If the problem is sore throat, however, ibuprofen should not be given to children under age 3 years. Furthermore, patients over age 65 years should consult a physician before use. Naproxen (e.g., Aleve) can be taken by patients over the age of 12 years. You should not give or take the safe dose for extended periods of time. The general time for safe use of nonprescription analgesics is five days in children (two days for sore throat) and 10 days in adults. If the pain is still present after this time, it is important to visit a physician to discover the source. Additionally, taking a product such as acetaminophen that seems safe for too long a period could cause fatal liver damage. While there are far too many warnings to include them all here, some should be mentioned. If you consume three or more alcoholic beverages daily, you should not take nonprescription analgesics. Aspirin, Aleve, and Motrin added to alcohol can cause severe stomach damage. Tylenol and alcohol together can cause severe, possibly fatal, liver damage. You should avoid aspirin if you have problems such as heartburn, upset stomach, stomach pain that persists or worsens, ulcers, or bleeding problems. You should not take acetaminophen if you have liver damage. You should avoid aspirin, ibuprofen, and naproxen during pregnancy and breastfeeding - this is critically important during the last three months of pregnancy, as these drugs can cause life-threatening bleeding problems for mother and child. Remember to carefully read all warnings on each product before taking it. As always, if you still have questions or concerns, consult with your physician or local pharmacist.

Skin rashes are common problems that affect many people throughout their lives. Rashes cause the skin to be abnormal in some way. It may appear red and will exhibit such changes as blisters, hives, drying, cracking, scaling, peeling, or swelling. There is usually itching or pain associated with the rash. The general term for skin rash is dermatitis, a word that refers to inflammation of the dermis, one of the layers of your skin.
There are thousands of possible causes for your rash, but they can be placed into several categories:
Allergic Contact Dermatitis: Your skin comes in contact with hundreds of substances every day, including chemicals, topical medications, poison ivy and other plants, laundry detergents, cleaning products, latex-containing products, dyes in clothing, rubber, cosmetics, soaps, etc. You may develop an allergy to any of these, causing the skin to break out in a rash. Contact dermatitis is usually extremely itchy.
Irritant Contact Dermatitis: This is due to various irritants that damage the skin, including exposure to acids or bases or to substances that leave irritants in the skin, such as insulation or okra pods. The damage can cause discomfort, ranging from mild irritation to severe pain.
Atopic Dermatitis: Some people develop a rash known as atopic dermatitis due to hereditary causes. Parents may notice that the child with atopic dermatitis has red, chapped cheeks with scaling patches on the arms, legs, body, and scalp. It seems to worsen in the winter and improve in the summer. The reason is that cold, dry winter air aggravates the condition. Skin is inflamed, with a lot of itching. It cannot be cured, but persists for the life of the individual.
Seborrheic Dermatitis: This rash is thought to be due to fungal invaders that irritate the skin where there is a lot of sebaceous activity (such as the hairline, forehead, eyebrows, eyelashes, eyelids, beard, mustache, external ear canal, and creases at the side of the nose). It causes scales that are yellow-red and greasy, and the skin is red, with itching and/or burning. It also persists for the entire life.
Medication-Induced Dermatitis: Medications you take internally can cause rash. If you have taken a medication before, and after starting it again develop a rash within a week or so, it may be caused by the medication. Do not discontinue the medication on your own. Rather, you should immediately ask the advice of the prescribing practitioner. If it is after office hours, the best advice is to contact him/her at home or visit an emergency room.
Call an emergency room only if you are having difficulty breathing, if you experience shortness of breath, if your face begins to swell, or if your throat gets tight. A purple rash that resembles a bruise may indicate a more serious condition.
For most minor rashes, you can consult your pharmacist. The pharmacist will know when to recommend self-treatment and when to suggest a physician visit. The pharmacist may suggest self-treatment with hydrocortisone, local anesthetics, or protectant ingredients.  Home blood pressure monitoring is an excellent way to take charge of your health. When done properly, it can help improve your hypertension and manage the efficacy of any antihypertensive medications you may be taking. Several types of home monitoring devices are available, each with its own advantages and disadvantages.There are numerous products for home blood pressure measurement. They vary by cost, difficulty in use, and portability. One type is the aneroid monitor, costing between $20 and $30. It has a cuff that is inflated by squeezing a rubber bulb. You read it by looking at a dial on a gauge that is located on the cuff. It is easy to carry from place to place. Unfortunately, the aneroid monitors are more prone to damage and may not provide an accurate reading if the damage goes undetected. Some aneroid monitors have a metal ring that makes it easier to fit them to the arm. If you are required to use a separate stethoscope with the aneroid monitor, it is important to check that you can hear the sounds through the stethoscope before purchase. The other popular type is the digital monitor. The cuffs of the monitor are inflated either manually or automatically, but they are all read by looking at a digital readout on a screen. If anything is not working correctly, an error message appears. The automatic digital monitors are considered easiest to use by most patients. Virtually all deflate automatically. They are more expensive than aneroid products (about $30 to $100), and batteries must be replaced periodically. Furthermore, movement can affect the accuracy of the reading.Some products claim to provide accurate measurement using only the finger or wrist. However, their accuracy is questionable, they are usually more expensive than other monitors, and body position and temperature can easily affect them. When you first purchase a monitor, it is a good idea to bring it to your next medical appointment and ask your health care provider to watch your technique to see if you are using it correctly. Your monitor can also be tested for accuracy by checking it against a blood pressure reading obtained at the office. Once a year, you should ask your health care provider to verify the accuracy of your monitor. Make sure that you store it carefully in a cool location, so heat will not ruin the rubber tubing or other parts. If the monitor will not hold air after you try to pump it up, it may need to be discarded. Remember, if you have questions, consult your pharmacist. 
Seasonal affective disorder, or SAD, is a type of depression that occurs each year around the same time, usually during the fall and winter months. SAD can occur during the summer also, but this is less common. The important difference between SAD and other forms of depression, such as major depression and bipolar depression, is that the depressive symptoms occur during only one season and are absent the rest of the year.The symptoms of SAD in the fall and winter are basically the same as those for other types of depression, including feelings of hopelessness, loss of interest in previously enjoyed activities, difficulty concentrating, and anxiety. These symptoms are often accompanied by oversleeping, low energy levels, increased appetite, and weight gain. People whose SAD occurs in the summer may be anxious, agitated, impatient, and irritable. This can lead to poor sleep habits, poor appetite, and weight loss. Some people with SAD treat their symptoms with drugs or alcohol, a risky behavior that only makes the depression worse. Anyone who suffers the symptoms of SAD each year should seek help from a doctor who is qualified to diagnose and treat depression. The diagnosis of SAD is made by determining that the symptoms have occurred for at least two years during the same season, that the symptoms disappear when the season is over, and that there is no other mental or physical health problem that could be the cause.Treatment for SAD can include light therapy, drug therapy, or behavioral psychotherapy, alone or in combination. Light therapy is used as a substitute for sunlight in winter SAD. In this therapy, the patient sits near a specially designed white fluorescent light box or wears a light visor that can be set to a certain brightness over a short period of time (usually 15 to 90 minutes) each day. The therapy works by simulating outdoor light, resulting in an improvement in mood, probably through changes in brain chemistry. Results are usually seen in a few days to several weeks. Light therapy works best if the light is administered early in the day. If used properly, light therapy has few side effects. Tanning beds or similar types of lighting should not be used to treat SAD since they do not have proper UV light filtration and are not designed to provide therapeutic light simulation.Antidepressant drug therapy also is successful for relieving the symptoms of SAD, and even for preventing them, if taken several weeks prior to the usual onset of symptoms and continued throughout the season. Bupropion is approved by the FDA for preventative therapy for SAD, and several other similar antidepressants are commonly prescribed for this condition, including fluoxetine, paroxetine, and sertraline. Antidepressants can potentially cause side effects, including drowsiness, nausea, anxiety, insomnia, and increased suicidal thoughts. These side effects must be taken into account whenever these drugs are considered for the treatment of SAD.Psychotherapy can be useful for patients by helping them learn healthy ways to cope with the mood changes associated with SAD. Although psychotherapy cannot change the biochemistry in the brain, it can be an important tool for keeping life more regular during the season in which the depression occurs. Stress management, regular exercise and social activities, vacations to warmer and sunnier climates in winter, and avoidance of self-medication with drugs or alcohol all can be important tools to keep SAD under control during the problem season.Although many people consider SAD to be merely the "winter blues", this type of depression can be serious if accompanied by self-medication with alcohol or drugs, thoughts of suicide, or withdrawal from others. These symptoms are a signal that the condition is more than just the blues - it is a serious form of depression that can be successfully treated.
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